Recombinant human erythropoietin counteracts cisplatin-induced visceral hyperalgesia
نویسندگان
چکیده
منابع مشابه
The Protective Effect of Recombinant Human Erythropoietin against Cisplatin-Induced Ototoxicity
Department of Otorhinolaryngology, Dokuz Eylul University School of Medicine, İzmir, Turkey (ED, YO, GK, EAG) Department of Laboratory of Animal Science, Dokuz Eylul University School of Medicine, İzmir, Turkey (EK, OY) Department of Basic Oncology, Dokuz Eylul University School of Medicine, İzmir, Turkey (PE, SA, ZA) Department of Biostatistics, Dokuz Eylul University School of Medicine, İzmir...
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BACKGROUND Human recombinant erythropoietin (rHuEpo) that is used for the treatment of the chemotherapy-induced anaemia in cancer patients was shown to cause detrimental effects on the course of disease due to increased adverse events inflicting patient's survival, potentially related to rHuEpo-induced cancer progression. In this study, we elucidate the effect of rHuEpo administration on breast...
متن کاملRe: Sex differences in protective effect of recombinant human erythropoietin against cisplatin-induced nephrotoxicity in rats.
INTRODUCTION The protective role of recombinant human erythropoietin (RHE) against cisplatin-induced nephrotoxicity has been reported, but the role of sex differences is not clearly known. The aim of this study was to determine the sex-based difference in the protective effect of RHE against cisplatin-induced nephrotoxicity. MATERIALS AND METHODS Thirty-three Wistar rats were divided into 6 g...
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Background: In patients undergoing chemotherapy for cancer, anemia is part of the progression of the disease. Considering the effects of anemia on quality of life of the patients, the prevention and treatment of chemotherapy-induced anemia is crucial. This study was aimed to evaluate the efficacy of recombinant human erythropoietin in reducing the need for blood transfusion in children with sol...
متن کاملVisceral Hyperalgesia
Visceral hyperalgesia refers to increased pain sensation in response to gastrointestinal sensory stimulus. In neonates with neurological impairments, gabapentin has been successfully used as a treatment for visceral hyperalgesia in neonates. The authors describe a preterm infant with myelomeningocele and persistent neuropathic pain that manifested as irritability, hypertonicity, poor weight gai...
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ژورنال
عنوان ژورنال: Neuroscience Bulletin
سال: 2010
ISSN: 1673-7067,1995-8218
DOI: 10.1007/s12264-010-0413-6